Journal: Journal of Cachexia, Sarcopenia and Muscle
Article Title: BIO101 in Sarcopenic Seniors at Risk of Mobility Disability: Results of a Double‐Blind Randomised Interventional Phase 2b Trial
doi: 10.1002/jcsm.13750
Figure Lengend Snippet: Change from baseline in 4‐m gait speed at Month 6 based on multiple imputation in the PP population. Missing data are imputed using multiple imputation. Analysis is based on mixed‐effect model for repeated measurements (MMRM) with treatment, visit, center, gender, and treatment * visit as fixed effects and baseline value as a covariate. LS, least square; SE, standard error.
Article Snippet: A mixed‐effects model repeated measurement (MMRM) model with fixed factors of treatment, centres, baseline score and sex was used (in SAS v9.3) to estimate the CFB of the 400MWT GS at Month 6/9 between each active arm and the placebo group (after adjustment for multiplicity due to the two doses of active treatment by the Hochberg procedure).
Techniques: